{"id":29,"date":"2026-08-17T12:53:22","date_gmt":"2026-08-17T12:53:22","guid":{"rendered":"https:\/\/peptide-doc.com\/learn\/selank\/"},"modified":"2026-09-02T19:41:50","modified_gmt":"2026-09-02T19:41:50","slug":"selank","status":"publish","type":"learn_article","link":"https:\/\/peptide-doc.com\/de\/learn\/selank\/","title":{"rendered":"Selank"},"content":{"rendered":"
\nMETA-TITLE:<\/strong> [TODO: Selank \u2014 Anxiolytic Peptide Research Profile | Brand]
\nMETA-DESC:<\/strong> [TODO: Selank research overview \u2014 tuftsin analog, anxiolytic without sedation, GABA\/serotonin modulation, immune peptide.]\n<\/div>\n

[TODO]<\/span> Hook \u2014 Selank as a synthetic tuftsin analog, anxiolytic without sedation or dependence, dual cognitive\/immune mechanism, prescribed in Russia<\/p>\n

[IMAGE: Selank molecular structure \u2014 Thr-Lys-Pro-Arg-Pro-Gly-Pro heptapeptide]<\/div>\n

What is Selank?<\/h2>\n
    \n
  • [TODO]<\/span> Full name \u2014 Selank, Thr-Lys-Pro-Arg-Pro-Gly-Pro (tuftsin + PGP)<\/li>\n
  • [TODO]<\/span> Origin \u2014 Institute of Molecular Genetics, Russian Academy of Sciences<\/li>\n
  • [TODO]<\/span> Base peptide \u2014 synthetic analog of tuftsin (natural immune peptide)<\/li>\n
  • [TODO]<\/span> Approved use \u2014 Russia (generalized anxiety disorder, neurasthenia)<\/li>\n
  • [TODO]<\/span> Administration \u2014 intranasal (primary)<\/li>\n<\/ul>\n

    Mechanism of Action<\/h2>\n
      \n
    • [TODO]<\/span> GABAergic \u2014 allosteric modulation of GABA-A receptors (benzodiazepine-like but without sedation)<\/li>\n
    • [TODO]<\/span> Serotonin \u2014 modulates 5-HT metabolism, increases serotonin availability<\/li>\n
    • [TODO]<\/span> Enkephalins \u2014 stabilizes enkephalin degradation, endogenous opioid pathway<\/li>\n
    • [TODO]<\/span> BDNF \u2014 increases expression (shared with Semax)<\/li>\n
    • [TODO]<\/span> Immune \u2014 tuftsin backbone, IL-6 modulation, NK cell activation<\/li>\n<\/ul>\n

      Research Highlights<\/h2>\n
        \n
      • [TODO]<\/span> Anxiety \u2014 equivalent to benzodiazepines in Russian clinical trials, without sedation\/addiction<\/li>\n
      • [TODO]<\/span> Cognitive \u2014 improved memory under stress, attention enhancement<\/li>\n
      • [TODO]<\/span> Immune \u2014 enhanced immune function via tuftsin-mediated phagocyte activation<\/li>\n
      • [TODO]<\/span> Gene expression \u2014 modulates 45 genes related to neurotransmission<\/li>\n
      • [TODO]<\/span> No tolerance \u2014 no dependence or withdrawal observed in studies<\/li>\n<\/ul>\n

        Dosing Protocols (Research Context)<\/h2>\n
          \n
        • [TODO]<\/span> Intranasal \u2014 250-500mcg\/day (1-3 drops per nostril, 2-3x daily)<\/li>\n
        • [TODO]<\/span> Subcutaneous \u2014 100-300mcg\/day<\/li>\n
        • [TODO]<\/span> N-Acetyl Selank \u2014 enhanced variant with improved stability<\/li>\n
        • [TODO]<\/span> Duration \u2014 14-21 day protocols typical<\/li>\n<\/ul>\n

          Safety & Considerations<\/h2>\n
            \n
          • [TODO]<\/span> No sedation, addiction, or cognitive impairment (key advantage over benzodiazepines)<\/li>\n
          • [TODO]<\/span> No withdrawal \u2014 can be discontinued abruptly<\/li>\n
          • [TODO]<\/span> Side effects \u2014 minimal; occasional mild nasal irritation<\/li>\n
          • [TODO]<\/span> Western data \u2014 limited clinical data outside Russian literature<\/li>\n<\/ul>\n

            Frequently Asked Questions<\/h2>\n
            [FAQ: Is Selank addictive like benzodiazepines?]<\/div>\n
            [FAQ: Can Selank be combined with Semax?]<\/div>\n
            [FAQ: How quickly does Selank take effect?]<\/div>\n
            [FAQ: What is the difference between Selank and N-Acetyl Selank?]<\/div>\n

            Related Products<\/h2>\n

            [TODO]<\/span> Link to Selank product page + Cognitive category<\/p>\n","protected":false},"excerpt":{"rendered":"

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